Hairy cell leukaemia

Hairy Cell Leukaemia

Hairy cell leukaemia is a rare haematological malignancy characterized by an accumulation of abnormal B lymphocytes. The affected B cells are abnormal and look "hairy" under a microscope, they accumulate in the bone marrow, interfering with the production of normal white blood cells, red blood cells, and platelets.

Recent studies have identified somatic BRAF V600E mutations in all patients with the classic form of hairy cell leukaemia thus sequenced, but in no patients with the variant form.

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